Back to David's theory of evolution: God's errors (Evolution)

by David Turell @, Tuesday, July 28, 2020, 19:36 (445 days ago) @ David Turell

Mistakes in genetic controls of the immune system causes auto-immune diseases:

"A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and celiac disease.


"Chronic immune diseases -- including type 1 diabetes, celiac disease and multiple sclerosis -- are caused by an overactive immune system and affect about 5 per cent of Australians. Allergies are immune-mediated too and affect one in five Australians, with hay fever, asthma, eczema, anaphylaxis and food allergies the most common. Inflammation and autoimmunity are also known to be driving factors in cardiovascular diseases, for example when an overactive immune system mistakenly attacks the heart.


"'Disease is partly due to changes, both large and small, in our genome -- the DNA that we're born with and which is a major driving force in all our cells. That means, genomics can be used to estimate disease risk from a very early age," Dr Inouye said.

"'Common diseases, such as type 2 diabetes and cardiovascular disease, tend to be polygenic -- influenced by a large number of genetic variants scattered throughout the genome, which combine with environmental and lifestyle factors. By using new genomic technology and supercomputing capabilities, we can sift through this DNA data and piece together the puzzles that underlie each disease.

"'With so many diseases sharing a root in the immune system and inflammation we can leverage this information to better understand where each disease has a molecular weak spot and to what extent these are shared among different diseases.

"'We've shown this can be dissected using genetics and polygenic risk, hopefully leading to targeted preventative interventions for those who need them most, with the aim of keeping people living healthier for longer.'"

Comment: Autoimmune diseases are mistakes of the genetic immune system. God has given us a brain that can solve many of the problems created.

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