Natures wonders: ant care for the sick protects well ants (Introduction)

by David Turell , Wednesday, February 21, 2018, 02:07 (2466 days ago) @ David Turell

Ants care for their sick mates in different ways depending on their level of immunity:

https://www.sciencedaily.com/releases/2018/02/180220161159.htm

"Ants care for their sick nest mates in different ways, depending on their own immune status. When they themselves are susceptible to dangerous superinfections, they use a different method to care for sick colony members compared to ants that are not susceptible, thus protecting themselves from infection.

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"There are two ways for ants to care for nest mates: either by grooming off pathogens or by chemically disinfecting them. However, the extensive contact between contaminated and caring ants during care may lead to a transmission of the pathogen, which often induces low-level infections in the caring individual that do not cause disease. As the research team has shown in a previous study, such low-level infections of the caring ants stimulate their immune system and can lead to a protective effect against future infection, similar to the early form of vaccination used by humans, termed variolation. If this ant comes in contact with the same pathogen again in the future, its defense against the fungal pathogen is already upregulated, and the course of the disease is mild. However, in the current study the research team showed that this immunization caused by low-level infections, unlike modern vaccinations in humans, has a cost. If the ant comes in contact with a second, different pathogen, it is not only unprotected, but is even more susceptible to the second pathogen, which can subsequently cause a highly detrimental, superinfection.

"Although ants with low-level infections are more susceptible to superinfections, the researchers show that this altered disease susceptibility affects how ants care for their infectious nest mates. They continue to perform care, but alter how they do so to decrease their risk of contracting a second infection. This risk avoidance is flexible and depends on the current immune status of the ant. If an ant is protected against a pathogen because it is currently immunized, it grooms the infected nestmate more than non-immunized ants. "This close contact means that the caring ant is exposed to a large number of fungal spores from the infectious nest mates, but it is less susceptible to them because of previous immune stimulation," explains Sylvia Cremer.

"The situation is different when the ant encounters a nest mate carrying a pathogen that the caring ant is susceptible to. If the ant has developed a susceptibility to pathogen B due to a previous infection with pathogen A, then it sprays the contaminated nestmate carrying pathogen B with formic acid to neutralize the pathogen. This avoids the need for grooming and the close contact that comes with it, preventing pathogen transmission and protecting the caring ant from superinfection. "This risk-averse care improves and maintains the health of the caring animals and thus of the whole colony. In humans, nursing staff and doctors also pay attention to their immune status, for example by vaccinating before entering a dangerous zone. Importantly, ants are capable of this adjustment without the need for vaccination records that humans typically rely on" explains Sylvia Cremer."

Comment: Ants social construct continues to amaze.