Introducing the brain: improve, preserve it, exercise more (Introduction)

by David Turell , Thursday, January 27, 2022, 20:51 (1029 days ago) @ David Turell

New study on young and old:

https://www.realclearscience.com/blog/2022/01/27/how_regular_exercise_restructures_the_...

"...physical activity can...buff up your brain. Science is increasingly revealing that the brains of those who regularly work out can look very different compared to the brains of people who don't.

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"...in 2018, researchers from the University of Southern California found that for teens aged 15-18, regular exercisers tended to have larger hippocampal volumes as well as larger rostral middle frontal volumes compared to healthy matched control teenagers. The hippocampus is most commonly associated with memory and spatial navigation, while the rostral middle frontal gyrus has been linked to emotion regulation and working memory. Studies suggest that these structural changes translate to improved cognitive performance and better academic outcomes.

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"The researchers recruited older African Americans, all previously sedentary, to complete twenty weeks of twice-weekly cardio-dance exercise classes held at local churches and senior centers. As compared to the control group comprised of community members of similar age and background who did not exercise, those in the program showed significant improvements in dynamic brain connectivity (or “neural flexibility”) in their hippocampus and surrounding medial temporal lobe, as measured using resting-state functional MRI.

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"Researchers have also tried exercise interventions on much older adults, even those with Alzheimer's disease, to see if physical activity could repair their stricken brains. In 2016, a team of scientists recruited 68 older individuals with probable Alzheimer's disease to determine whether moving more could help with their symptoms. Some subjects aerobically exercised for 150 minutes per week while others underwent a less rigorous control regimen of stretching and toning for 26 weeks. Compared to the control group, the aerobic exercise group improved more on the Disability Assessment for Dementia at the study's conclusion. Boosts to cardiorespiratory fitness were also linked to improvements in memory and reduced atrophy of the hippocampus.

"Working out also augments the brains of otherwise healthy older adults. Getting thirty minutes of physical activity each day does seem to preserve brain volumes in adults over age 70 compared to sedentary individuals, according to a study published in August of last year. Moreover, higher cardiorespiratory fitness was linked to lower levels of brain atrophy in the research.

"One way exercise can induce changes in the brain is by increasing levels of the protein brain-derived neurotrophic factor (BDNF) in the blood, which is linked to neurogenesis. More BDNF may mean more new neurons in the brain. Regular exercise also increases the growth of additional blood vessels in the brain and helps maintain current ones, leading to boosted blood flow for the oxygen-hungry organ. Lastly, physical activity seems to keep microglia in good working order. Microglia "constantly check the brain for potential threats from microbes or dying or damaged cells and clear any damage they find," Áine Kelly, a Professor in Physiology at Trinity College Dublin wrote."

Comment: Keep moving!!