brain;complexity: structure of a hippocampal receptor (Introduction)

by David Turell @, Sunday, April 14, 2019, 21:28 (71 days ago) @ David Turell

Look at the diagram to see the complex structure:

https://www.sciencedaily.com/releases/2019/04/190411145131.htm

"The new research, published in the journal Science, is the first to reveal the structure of AMPA receptors in their natural state. This discovery could lead to new insight about the mechanism behind a wide range of nervous system disorders and diseases.

"'These are the fundamental electrical switches of the brain," said senior author Eric Gouaux, Ph.D., senior scientist and Jennifer and Bernard LaCroute Term Chair of neuroscience in the OHSU Vollum Institute and an investigator for the Howard Hughes Medical Institute. "If these switches don't work right, then the brain doesn't function.

***

"AMPA receptors are activated by the neurotransmitter glutamate, forming permeable ion channels that carry signals between cells throughout the nervous system."

Comment: The importance of this discovery for medical science is that it will hopefully help finding cures for disease defects. The importance as far as the Darwin theory is concerned is that it is impossible to have developed a protein of this complex structure and function by Darwin's proposed chance mechanism. It must be designed all at once to fill its purpose. Hunt and peck trial and error attempts over many chance mutations reasonably cannot work. At each point it must be tested by natural selection for proper function, and how does the organism survive each failure? The alternative is every new step is an unqualified success. Really?


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