Immunity system complexity: special T cells in brain (Introduction)
by David Turell 
, Wednesday, September 04, 2024, 19:44 (79 days ago) @ David Turell
Found in brain tumors:
https://www.nature.com/articles/s41591-024-03152-x?utm_source=Live+Audience&utm_cam...
"The human brain is usually considered to be beyond the reach of most immune cells. However, analysis of people who have a type of brain tumour called glioblastoma has revealed tumour-targeting T cells in the skull bone marrow adjacent to the tumour. Some of the characteristics of the cells hint that they’re something special. For example, their high expression of sphingosine-1-phosphate receptor 1 (S1PR1) protein, which signals to T cells to go out on the hunt, that the skull bone might serve as a reservoir for immune cells. And T cells isolated from skull bone marrow remain activated after rounds of restimulation — avoiding ‘exhaustion’, which is one of the main obstacles to immunotherapy."
Comment: just an article summary. Finding those cells is a surprise. S1PR1 protein implies design.
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2022-12-24, 15:44
- Immunity system complexity: supporting T cells. -
David Turell,
2023-01-13, 18:26
- Immunity system complexity: T cells. support neurons -
David Turell,
2023-01-14, 15:48
- Immunity system complexity: innate and secondary -
David Turell,
2023-01-19, 22:15
- Immunity system complexity: innate and secondary -
David Turell,
2023-01-21, 19:49
- Immunity system complexity: control of reactions -
David Turell,
2023-02-03, 18:25
- Immunity system complexity: detecting infections -
David Turell,
2023-02-05, 22:28
- Immunity system complexity: detecting danger in C elegans - David Turell, 2024-11-12, 19:05
- Immunity system complexity: detecting infections -
David Turell,
2023-02-05, 22:28
- Immunity system complexity: control of reactions -
David Turell,
2023-02-03, 18:25
- Immunity system complexity: innate and secondary -
David Turell,
2023-01-21, 19:49
- Immunity system complexity: innate and secondary -
David Turell,
2023-01-19, 22:15
- Immunity system complexity: T cells. support neurons -
David Turell,
2023-01-14, 15:48
- Immunity system complexity: supporting T cells. -
David Turell,
2023-01-13, 18:26
- Immunity system complexity: ramping up B cells -
David Turell,
2022-12-24, 15:44
- Immunity system complexity: ramping up B cells -
David Turell,
2022-12-23, 18:43
- Immunity system complexity: superchargng T cells -
David Turell,
2022-12-23, 01:32
- Immunity system complexity: early evolution -
David Turell,
2022-09-27, 21:21
- Immunity system complexity: aging T cells don't fade away -
David Turell,
2022-09-23, 18:17
- Immunity system complexity: aging T cells don't fade away -
David Turell,
2022-09-22, 01:12
- Immunity system complexity: keeping fungus at bay -
David Turell,
2022-09-21, 17:52
- Immunity system complexity: keeping T cells ageless -
David Turell,
2022-09-15, 18:36
- Immunity system complexity: spotting attackers in bacterias -
David Turell,
2022-09-02, 19:40
- Immunity system complexity: spotting attackers -
David Turell,
2022-08-22, 17:30
- Immunity system complexity: more on T cell controls -
David Turell,
2022-08-15, 22:21
- Immunity system complexity: specialized corneal T cells -
David Turell,
2022-06-06, 20:08
- Immunity system complexity: glia cells everywhere -
David Turell,
2022-06-03, 19:25
- Immunity system complexity: how bacterial ssytem works -
David Turell,
2022-06-02, 20:10
- Immunity system complexity: special brain coverage -
David Turell,
2022-06-02, 00:26
- Immunity system complexity: B & T cell training -
David Turell,
2022-06-01, 19:54
- Immunity system complexity: T cell maintenance -
David Turell,
2022-05-28, 18:51
- Immunity system complexity: T cell differentiating daughters -
David Turell,
2022-05-20, 22:51
- Immunity system complexity: T cell differentiating enemies -
David Turell,
2022-05-20, 17:20
- Immunity system complexity: a B cell is found, new -
David Turell,
2022-05-13, 17:54
- Immunity system complexity: macrophage spread -
David Turell,
2022-04-23, 19:47
- Immunity system complexity: T c ell activity -
David Turell,
2022-04-16, 20:36
- Immunity system complexity: protecting the brain -
David Turell,
2022-03-17, 14:07
- Immunity system complexity: telling self from non-self -
David Turell,
2022-02-15, 17:35
- Immunity system complexity: innate immunity at work -
David Turell,
2023-01-28, 17:49
- Immunity system complexity:innate immunity NK cells at work -
David Turell,
2023-02-10, 18:53
- Immunity system complexity: transfers at birth - David Turell, 2023-02-13, 19:46
- Immunity system complexity:innate immunity NK cells at work -
David Turell,
2023-02-10, 18:53
- Immunity system complexity: how chlamydia escapes detection -
David Turell,
2023-02-23, 18:12
- Immunity system complexity: how B cells recognize antigens -
David Turell,
2023-03-10, 20:46
- Immunity system complexity: control dangerous bugs in gut -
David Turell,
2023-03-13, 22:53
- Immunity system complexity: gasdermin-B reviewed -
David Turell,
2023-03-30, 18:45
- Immunity system complexity: sentinel cell activation -
David Turell,
2023-03-31, 23:37
- Immunity system complexity: the role of IgA -
David Turell,
2023-05-30, 17:20
- Immunity system complexity: triggering inflammation -
David Turell,
2023-06-17, 18:22
- Immunity system complexity: fungal spore defense -
David Turell,
2023-06-21, 02:54
- Immunity system complexity: cellular viral defenses -
David Turell,
2023-06-28, 19:59
- Immunity system complexity: neutrophile activation -
David Turell,
2023-06-30, 17:59
- Immunity system complexity: skin protections -
David Turell,
2023-07-04, 15:16
- Immunity system complexity: triggering protein -
David Turell,
2023-07-26, 22:11
- Immunity system complexity: the brain's involvement -
David Turell,
2023-07-27, 18:36
- Immunity system complexity: new T cell triggers -
David Turell,
2023-08-19, 16:40
- Immunity system complexity: special T cells im cornea -
David Turell,
2023-08-23, 19:39
- Immunity system complexity: T cell triggers to fight cancer -
David Turell,
2023-09-30, 18:48
- Immunity system complexity: protecting pregnancy -
David Turell,
2023-11-14, 22:38
- Immunity system complexity: how bacteria fight phages -
David Turell,
2023-11-15, 19:30
- Immunity system complexity: how lipids help -
David Turell,
2023-11-27, 20:22
- Immunity system complexity: more B cell functions -
David Turell,
2023-11-27, 21:02
- Immunity system complexity: why fever -
David Turell,
2023-11-28, 19:27
- Immunity system complexity: bacterial molecular attacks -
David Turell,
2023-12-12, 18:42
- Immunity system complexity: response to flu vacines -
David Turell,
2023-12-22, 16:12
- Immunity system complexity: specialized T cells -
David Turell,
2023-12-29, 00:48
- Immunity system complexity: specialized T cells -
David Turell,
2024-01-03, 16:35
- Immunity system complexity: preventing kidney stones -
David Turell,
2024-01-08, 17:51
- Immunity system complexity: gut immune cells imporrtance -
David Turell,
2024-01-09, 15:42
- Immunity system complexity: production at high speed -
David Turell,
2024-01-12, 18:30
- Immunity system complexity: killer T cells promote repair -
David Turell,
2024-01-16, 20:40
- Immunity system complexity: helps digest chitin -
David Turell,
2024-01-17, 17:27
- Immunity system complexity: bacterial spears -
David Turell,
2024-01-18, 18:25
- Immunity system complexity: bacterial spears -
David Turell,
2024-01-18, 18:26
- Immunity system complexity: RNA guiding neutrophiles -
David Turell,
2024-01-22, 18:24
- Immunity system complexity: a new function of B cells -
David Turell,
2024-02-10, 20:20
- Immunity system complexity: guiding cells to infections -
David Turell,
2024-02-18, 19:18
- Immunity system complexity: T cells to attack or not -
David Turell,
2024-03-10, 20:31
- Immunity system complexity: RNA guides T cells -
David Turell,
2024-04-02, 17:55
- Immunity system complexity: pre-programmed T cells -
David Turell,
2024-06-07, 14:30
- Immunity system complexity: a functional DNA fragment -
David Turell,
2024-06-10, 17:18
- Immunity system complexity: controls of cell death -
David Turell,
2024-06-16, 22:15
- Immunity system complexity: brain stem controls -
David Turell,
2024-06-19, 18:11
- Immunity system complexity: special T cells in brain -
David Turell,
2024-09-04, 19:44
- Immunity system complexity: thanks to Asgard Archaea -
David Turell,
2024-09-08, 17:05
- Immunity system complexity: DNA hunts pathogens -
David Turell,
2024-09-22, 17:13
- Immunity system complexity: macrophages repair lungs - David Turell, 2024-10-09, 17:59
- Immunity system complexity: DNA hunts pathogens -
David Turell,
2024-09-22, 17:13
- Immunity system complexity: thanks to Asgard Archaea -
David Turell,
2024-09-08, 17:05
- Immunity system complexity: special T cells in brain -
David Turell,
2024-09-04, 19:44
- Immunity system complexity: brain stem controls -
David Turell,
2024-06-19, 18:11
- Immunity system complexity: controls of cell death -
David Turell,
2024-06-16, 22:15
- Immunity system complexity: a functional DNA fragment -
David Turell,
2024-06-10, 17:18
- Immunity system complexity: pre-programmed T cells -
David Turell,
2024-06-07, 14:30
- Immunity system complexity: RNA guides T cells -
David Turell,
2024-04-02, 17:55
- Immunity system complexity: T cells to attack or not -
David Turell,
2024-03-10, 20:31
- Immunity system complexity: guiding cells to infections -
David Turell,
2024-02-18, 19:18
- Immunity system complexity: a new function of B cells -
David Turell,
2024-02-10, 20:20
- Immunity system complexity: RNA guiding neutrophiles -
David Turell,
2024-01-22, 18:24
- Immunity system complexity: bacterial spears -
David Turell,
2024-01-18, 18:26
- Immunity system complexity: bacterial spears -
David Turell,
2024-01-18, 18:25
- Immunity system complexity: helps digest chitin -
David Turell,
2024-01-17, 17:27
- Immunity system complexity: killer T cells promote repair -
David Turell,
2024-01-16, 20:40
- Immunity system complexity: production at high speed -
David Turell,
2024-01-12, 18:30
- Immunity system complexity: gut immune cells imporrtance -
David Turell,
2024-01-09, 15:42
- Immunity system complexity: preventing kidney stones -
David Turell,
2024-01-08, 17:51
- Immunity system complexity: specialized T cells -
David Turell,
2024-01-03, 16:35
- Immunity system complexity: specialized T cells -
David Turell,
2023-12-29, 00:48
- Immunity system complexity: response to flu vacines -
David Turell,
2023-12-22, 16:12
- Immunity system complexity: bacterial molecular attacks -
David Turell,
2023-12-12, 18:42
- Immunity system complexity: why fever -
David Turell,
2023-11-28, 19:27
- Immunity system complexity: more B cell functions -
David Turell,
2023-11-27, 21:02
- Immunity system complexity: how lipids help -
David Turell,
2023-11-27, 20:22
- Immunity system complexity: how bacteria fight phages -
David Turell,
2023-11-15, 19:30
- Immunity system complexity: protecting pregnancy -
David Turell,
2023-11-14, 22:38
- Immunity system complexity: T cell triggers to fight cancer -
David Turell,
2023-09-30, 18:48
- Immunity system complexity: special T cells im cornea -
David Turell,
2023-08-23, 19:39
- Immunity system complexity: new T cell triggers -
David Turell,
2023-08-19, 16:40
- Immunity system complexity: the brain's involvement -
David Turell,
2023-07-27, 18:36
- Immunity system complexity: triggering protein -
David Turell,
2023-07-26, 22:11
- Immunity system complexity: skin protections -
David Turell,
2023-07-04, 15:16
- Immunity system complexity: neutrophile activation -
David Turell,
2023-06-30, 17:59
- Immunity system complexity: cellular viral defenses -
David Turell,
2023-06-28, 19:59
- Immunity system complexity: fungal spore defense -
David Turell,
2023-06-21, 02:54
- Immunity system complexity: triggering inflammation -
David Turell,
2023-06-17, 18:22
- Immunity system complexity: the role of IgA -
David Turell,
2023-05-30, 17:20
- Immunity system complexity: sentinel cell activation -
David Turell,
2023-03-31, 23:37
- Immunity system complexity: gasdermin-B reviewed -
David Turell,
2023-03-30, 18:45
- Immunity system complexity: control dangerous bugs in gut -
David Turell,
2023-03-13, 22:53
- Immunity system complexity: how B cells recognize antigens -
David Turell,
2023-03-10, 20:46
- Immunity system complexity: how T cells are triggered -
David Turell,
2023-10-25, 16:27
- Immunity system complexity: role of Vitamin D and gut biome - David Turell, 2024-07-21, 18:59
- Immunity system complexity: sniffing out invaders -
David Turell,
2024-11-20, 22:51
- Immunity system complexity: development in the fetus - David Turell, 2024-11-22, 21:54
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-09, 08:34
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-08, 15:06
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-08, 11:29
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-07, 18:24
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-07, 09:38
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-06, 19:51
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-06, 13:20
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-05, 15:24
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-05, 09:27
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-04, 15:03
- Immunity system complexity: controlling gut biome -
David Turell,
2021-10-13, 18:51
- Immunity system complexity: how T c ells kill - David Turell, 2021-10-14, 20:07
- Immunity system complexity: controlling gut biome - David Turell, 2022-02-28, 19:31
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-04, 12:21
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-03, 17:52
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-03, 12:57
- Immunity system complexity: B cell controls - David Turell, 2021-09-23, 18:05
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-02, 14:57
- Immunity system complexity: trained reactions in non-immune - David Turell, 2021-07-27, 19:24
- Immunity system complexity: how T cells are triggered -
dhw,
2019-04-02, 10:45
- Immunity system complexity: red cells are a part of it -
David Turell,
2021-10-21, 16:13
- Immunity system complexity: viruses fight our immunity -
David Turell,
2022-10-26, 00:08
- Immunity system complexity: viruses fight bat immunity -
David Turell,
2022-11-24, 17:17
- Immunity system complexity: viruses fight with CRISPR - David Turell, 2022-11-24, 19:48
- Immunity system complexity: viruses fight bat immunity -
David Turell,
2022-11-24, 17:17
- Immunity system complexity: viruses fight our immunity -
David Turell,
2022-10-26, 00:08
- Immunity system complexity: how T cells are triggered -
David Turell,
2019-04-01, 20:04
- Immunity system complexity -
David Turell,
2019-02-15, 01:42
- Immunity in humans; Bad antibodies are really good -
David Turell,
2018-04-20, 19:45
- Immunity in humans; fetal development -
David Turell,
2017-06-15, 18:45
- Immunity in humans; long term immunity from plasma cells -
David Turell,
2017-02-21, 21:45
- Immunity in humans; fungus protections are innate -
David Turell,
2016-12-20, 00:30