Genome complexity: how ribosomes work (Introduction)

by David Turell , Thursday, July 08, 2021, 17:19 (1022 days ago) @ David Turell

Picking apart the molecular mechanism:

https://phys.org/news/2021-07-capture-ribosome-action.html

The ribosome is the cellular organelle responsible for decoding messenger RNA to make proteins. Many antibiotics target the ribosome;...

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Expression of the information encoded in DNA makes life possible. DNA is first transcribed into RNA; RNA is then translated into protein. The ribosome is the molecular machine responsible for this second step. It decodes messenger RNA and makes proteins. Importantly, the ribosome is responsible for the synthesis of cellular proteins in all forms of life.

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Using these techniques, the researchers captured six high-resolution structures of the bacterial ribosomal complex, including messenger RNA, transfer RNA and elongation factor EF-G, an enzyme involved in reading RNA. The work reveals for the first time how EF-G engages with the ribosome complex. (my bold)

Comment:

Such complexity has to be designed, especially the enzyme noted in my bold. Enzymes are giant molecules of many amino acids in precise order to drive the reaction.