Theoretical origin of life: identifying basic proteins (Introduction)

by David Turell , Monday, January 17, 2022, 19:40 (1041 days ago) @ David Turell

Metal containing proteins are analyzed finding basic building blocks that theoretically were a basic starting group:

https://www.sciencedaily.com/releases/2022/01/220114153440.htm

"The researchers explored how primitive life may have originated on our planet from simple, non-living materials. They asked what properties define life as we know it and concluded that anything alive would have needed to collect and use energy, from sources such as the Sun or hydrothermal vents.

"In molecular terms, this would mean that the ability to shuffle electrons was paramount to life. Since the best elements for electron transfer are metals (think standard electrical wires) and most biological activities are carried out by proteins, the researchers decided to explore the combination of the two -- that is, proteins that bind metals.

"They compared all existing protein structures that bind metals to establish any common features, based on the premise that these shared features were present in ancestral proteins and were diversified and passed down to create the range of proteins we see today.

"Evolution of protein structures entails understanding how new folds arose from previously existing ones, so the researchers designed a computational method that found the vast majority of currently existing metal-binding proteins are somewhat similar regardless of the type of metal they bind to, the organism they come from or the functionality assigned to the protein as a whole. (my bold)

"'We saw that the metal-binding cores of existing proteins are indeed similar even though the proteins themselves may not be," said the study's lead author Yana Bromberg, a professor in the Department of Biochemistry and Microbiology at Rutgers University-New Brunswick. "We also saw that these metal-binding cores are often made up of repeated substructures, kind of like LEGO blocks. Curiously, these blocks were also found in other regions of the proteins, not just metal-binding cores, and in many other proteins that were not considered in our study. Our observation suggests that rearrangements of these little building blocks may have had a single or a small number of common ancestors and given rise to the whole range of proteins and their functions that are currently available -- that is, to life as we know it.'"

Comment: designing basic starting proteins and building from there is a standard design plan for future development. The bold about one step leading to another is what dhw's complaints always seem to skip or minimize. This is a standard article without mentioning God. For me it shows God's planning at the beginning of life.