Junk DNA: goodbye!: ENCODE now hedging on 80% (Introduction)

by Balance_Maintained , U.S.A., Sunday, May 10, 2020, 23:43 (1445 days ago) @ David Turell

" A spatial understanding of how DNA is packaged into a cell, and of the 3D folding that positions genes in close contact with their regulatory elements(emphasis mine), will be key to predicting an element's target genes. The NIH Common Fund has begun the '4D Nucleome' project, for instance, which aims to predict the target genes for every regulatory element. That knowledge will help to fill in the picture of how a given regulatory element influences health and disease."

I know this is an old post, but a particular line caught my eye. What regulates the protein folding spatially? What puts the protein in close proximity to the right regulatory section? How is the information of that spatial awareness stored?

--
What is the purpose of living? How about, 'to reduce needless suffering. It seems to me to be a worthy purpose.