Genome complexity in embryology: egg starting (Introduction)

by Balance_Maintained , U.S.A., Thursday, July 13, 2017, 05:53 (2691 days ago) @ David Turell

David
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"When an egg is activated, levels of another enzyme that adds phosphates to GNU in the egg precipitously drop, allowing GNU to lose its phosphates and bind to PNG-PLU. Once together, the trio comprises the PNG kinase that triggers the translational control of the maternal mRNAs. Because PNG kinase also triggers the break down of GNU, the kinase self-destructs, which quickly and irreversibly squelches the translation of maternal mRNAs. This elegant feedback loop and the switch it controls are described in an article in eLife. (my bold)

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"Although she now has as greater understanding of how translation is turned on and off during very early embryonic development, Orr-Weaver is intrigued by how the switch is linked to the translation machinery.

"'PNG is a kinase, which means it controls things by what it phosphorylates," says Orr-Weaver, who is also an American Cancer Society Research Professor of biology at MIT. "So the big question is what proteins does it phosphorylate? Finding that out is the next big phase of this project.'"

Comment: Note my bold. A feedback loop must develop all at once with all of it. The enzyme is a giant molecule. Evolution did not hunt and peck for it. It has a specific purpose fro which it is designed. That is the key point. A system like this requires a designer!

You know, it is getting to the point where I don't even feel the need to argue for God here because you are doing such a beautiful job of it for me.

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What is the purpose of living? How about, 'to reduce needless suffering. It seems to me to be a worthy purpose.