Genome complexity: RNA controls (Introduction)

by David Turell @, Thursday, February 21, 2013, 15:32 (2219 days ago) @ David Turell

Destroying or organizing RNA in a cell is up to the exosome, a conplex set of organic molecules. Exactly how it works is not fully understood, but it exists in all forms of cellular life, conseved at all levels of evolution:

"Any errors that occur during the synthesis of RNA molecules or unwanted accumulation of RNAs can be damaging to the cell. The elimination of defective RNAs or of RNAs that are no longer needed are therefore key steps in the metabolism of a cell. The Exosome, a multi-protein complex, is a key machine that shreds RNA into pieces. In addition, the Exosome also processes certain RNA molecules into their mature form. However, the molecular mechanism of how the Exosome performs these functions has been elusive."

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