The biochemistry of cell adhesion and communication (Introduction)

by David Turell , Saturday, December 19, 2015, 00:40 (3262 days ago) @ dhw

DAVID: We have discussed inter-cellular communication. This article shows how a series of molecular cascade reactions tell a cell it has adhered to its neighbor and receives communication to act upon
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> http://www.mechanobio.info/modules/go-0007229
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> David's comment: A highly complex biochemistry article, but what it says is cells communicate and adhere thru a series of molecular cascade reactions. All of this easily follows instructional information organization, using the natural functional reactions of protein molecules. Shapiro et al. work at the single cell level, and their discussion only covers that level of biochemistry.
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> dhw" We all know that cells communicate, and we also know that cells form communities. I don't understand your comment about Shapiro et al. Are you implying they don't realize that communication requires partners, and cells work in communities?-My point about Shapiro et al is they work with single-celled animals, not whole animals or whole organs. Shapiro's observations and theories are all based on single-cell studies. He does not look at communities nor comment on communities of cells in his book. I thought I was very clear. Of course he understands how organs and bodies work, but he doesn't discuss the 'intelligence' of kidney cells, or do I know if he would extrapolate his theory into how kidney cells apply intelligence.