Irreducible complexity: mitotic spindle orientation (Introduction)

by David Turell , Monday, January 11, 2016, 22:26 (3037 days ago) @ David Turell

The Wash Post is now touting this as the cause of multicellularity!-https://www.washingtonpost.com/news/morning-mix/wp/2016/01/11/startling-new-discovery-600-million-years-ago-a-single-biological-mistake-changed-everything/?wpmm=1&wpisrc=nl_evening-"In a paper published in the open-access journal eLife this week, researchers say they have pinpointed what may well be one of evolution's greatest copy mess-ups yet: the mutation that allowed our ancient protozoa predecessors to evolve into complex, multi-cellular organisms. Thanks to this mutation — which was not solely responsible for the leap out of single-cellular life, but without which you, your dog and every creature large enough to be seen without a microscope might not be around — cells were able to communicate with one another and work together.-"Incredibly, in the world of evolutionary biology, all it took was one tiny tweak, one gene, and complex life as we know it was born.-“'It was a shock,” co-author Ken Prehoda, a biochemist at the University of Oregon, told The Washington Post. “If you asked anyone on our team if they thought one mutation was going to be responsible for this, they would have said it doesn't seem possible.”-***-"But it turned out that only one was needed: A single mutation that repurposed a certain type of protein. Instead of working as enzymes (proteins that facilitate reactions inside the cell) the proteins were now what's known as an interaction domain. They could communicate with and bind to other proteins, a useful skill for cells that have decided to trade the rugged individualist life for the collaboration of a group. In the wild world of pre-complex life, this development was orders of magnitude better than Twitter for getting organisms organized. Every example of cells collaborating that has arisen since — from the trilobites of 500 million years ago to the dinosaurs, woolly mammoths and you — probably relied on it or some other similar mutation." (my bold)-Comment: I'm sure this mutation was very important but look at the bolded comment above. Always overoptimistic. It undoubtedly required more than just this.