Front end loading (Introduction)

by David Turell , Wednesday, October 08, 2008, 01:43 (5680 days ago) @ David Turell

I was notified about an online discussion for newly discovered RNA molecules with different functions: - "Non-coding RNAs (ncRNAs) are a large group of RNAs that are transcribed, but not translated into protein. They include well-characterized transfer RNAs and ribosomal RNAs, as well as newer and more elusive miRNAs which have been shown to play a crucial role in gene regulation. ncRNAs produce functional RNA molecules rather than encoding proteins and have been found to have roles in a plethora of cellular processes including transcriptional regulation, RNA processing and modification, mRNA stability, and even protein degradation. Even though a large number of genomes have been sequenced, the number and diversity of ncRNA-encoding genes is largely unknown. Many more ncRNAs have been discovered than were predicted, with recent transcriptomic and microarray studies suggesting that, for the mouse genome alone, there exists more than 30,000 long ncRNAs. The challenge now facing researchers is to determine the size of the full compliment of ncRNAs, as well as elucidate their function, particularly in disease. This online discussion will center on the different forms of ncRNAs, and the roles they may play in the biology and pathology of human disease." - The mouse genome contains more functional RNA numerically than the genes themselves. Imagine what our genome will turn up when this research into the different RNA's is completed. This is a master code within a master code. Layer after layer of functionality. Human experience with coding inplies intelligent planning and activity. It still looks like front end loading to me.