genome evolution (Introduction)

by David Turell , Tuesday, February 25, 2014, 15:44 (3924 days ago)

Trying to determine how intformation and patterns changed from early evolution to later. Note life is based on information:-"The pair is using a technique called phylometabolic analysis, which combines the building of gene-based family trees of relatedness (called phylogenies) with reconstruction of chemical metabolic networks. This lets the researchers "see not just what information is changing, but how specific driving forces are changing the underlying chemical networks encoded by those genes," explains Braakman. (my bold)
 
Their research, published February 5 in PLOS ONE, highlights three main drivers of evolution: optimizing kinetics, either by replacing generalist enzymes with multiple, specialized enzymes or by fusing successive enzymes in a pathway together to minimize diffusion; and optimizing thermodynamics by choosing pathways that use less energy. These drivers, they say, evoke a major tradeoff in evolution ... speed versus efficiency ... and suggest that early ancestors probably started with a smaller assortment of enzymes, each of which could weakly catalyze many different reactions."-
 Read more at: http://phys.org/news/2014-02-chemical-subsystems-metabolism.html#jCp