Genome complexity: DNA repair mechanisms (Introduction)

by David Turell @, Thursday, October 22, 2015, 13:20 (3080 days ago) @ David Turell

The Nobel prize in chemistry goes to three scientists who worked out a major part of an incomplete story of excision of DNA when a mismatch occurs in cell division and DNA copying:- http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/popular-chemistryprize2... is an excellent article in lay terms with great diagrams. Just remember that the enzymes used are giant molecules, which raises the obvious question: if chance evolution is true, how did evolution find each very specialized molecule made up of thousands of amino acids and trace metals?- "Our DNA remains astonishingly intact, year after year, due to a host of molecular repair mechanisms:a swarm of proteins that monitor the genes. They continually proof-read the genome and repair any damage that has occurred. The Nobel Prize in Chemistry 2015 is awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for having mapped these fundamental processes at the molecular level. Their systematic work has made a decisive contribution to the understanding of how the living cell functions, as well as providing knowledge about the molecular causes of several hereditary diseases and about mechanisms behind both cancer development and aging."


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