Genome complexity: copying from DNA (Introduction)

by David Turell , Tuesday, August 25, 2015, 14:24 (3157 days ago) @ David Turell

Remaking machinery constantly to make copies:-http://www.sciencedaily.com/releases/2015/08/150825083923.htm-"This machine is built afresh, moment by moment as it's needed during the copying process. This assembly-de-assembly is vital to accurate and efficient copying.-***-"Our DNA is stored as two strands that are tightly twisted together and joined like a zip. The most important information sits in the middle of this twisted structure, or in the teeth of the zip, where it's protected from harm. To copy this information, the strands need to be temporarily pulled apart. To do this, the cell recruits a large number of proteins and assembles them into a complex copying machine. A key component in the machine is a ring-shaped enzyme, called DNA helicase, which acts a bit like the clasp on a zip that allows you do it up or un-do it. The helicase unzips the DNA by binding to a strand and pulling it through the centre of its ring, but it is not yet known exactly how the helicase binds to the DNA strand.-"It was thought that Cdc6 acts like a tiny motor to place the helicase on top of the strand. Speck and his collaborators have overturned this theory by showing that the helicase can still get into position even when the Cdc6 motor is turned off. However, without active Cdc6, the cell was unable to proceed to the next stage in the copying process -- the machine was jammed. This showed Cdc6 is vital for the machine to function, but it was still not clear exactly what it does.-"The study shows that, once the early stages of copying have begun, the Cdc6 motor is required for removal of the helicase assembly machine. When the researchers inactivated the Cdc6 motor, the machine remained in place for too long."-Comment: How did this complexity develop step by step? I think it had theistic help.