Early embryology;merging male and female DNA (Introduction)

by David Turell @, Wednesday, April 01, 2015, 15:17 (3285 days ago) @ David Turell

Sperm meets egg, DNA's mix. This is how they merge:-http://phys.org/news/2015-04-heterochromatin-formation-onset-life.html-"Antoine Peters and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have elucidated the mechanisms controlling the packaging of chromatin in the early embryo. They have identified two molecular pathways that direct heterochromatin formation around centromeres in a manner dependent on the parental origin of the DNA.
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"These findings are noteworthy as they reflect differences in the preparation of chromatin for fertilization during male and female gametogenesis. During the development of the male gamete, the DNA packaging is substantially altered so that the whole genome can fit in the tiny head of the sperm. After fertilization, the packaging of paternal DNA is reprogrammed, in a series of steps, to the canonical form present in oocytes and somatic cell types. As the embryo grows, the differences between maternal and paternal chromatin thus disappear. Peters comments: "We are intrigued by the remarkable diversity in heterochromatin formation at the onset of life. Our current research is focusing on how the mechanisms described may contribute to gene regulation during early embryogenesis.'"- Read more at: http://phys.org/news/2015-04-heterochromatin-formation-onset-life.html#jCp -I show the embryologic molecular genetic reactions to illustrate just how complex the biochemistry has to be. And tell me how this developed by chance.


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